Effect of Salicylic Acid on the Early Development of the Chick Limb-Bud
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Cyclosporine Effects on Chick Limb Bud Mesenchyme and DNA Content
Background: Cyclosporine A (CsA) is a powerful immunosuppressive agent, which is used for the prevention of allograft rejection and for the treatment of autoimmune diseases. Many transplant recipients must take this medicine for the rest of their lives. Females in reproductive age group on prolonged CsA therapy have legitimate concerns about drug effects on pregnancy. Objective: To explore Cs...
متن کاملThe Effect of Salicylic Acid and Zinc on Inflorescence Bud Abscission, Leaf Chlorophyll Florescence and Characteristic of Pistachio Nut Cv. Owhadi
In order to determine effect salicylic acid and Zn on characteristics of pistachio nut (Pistacia vera L. cv. Owhadi), the experiment was carried out as factorial in the framework of CRD design with three replications. The results showed that salicylic acid and Zn increased nut fresh weight and decreased blank nut percentage. The application of salicylic acid decreased splitting percentage and k...
متن کاملاثرات مورفوژنیک و تراتوژنیک اسید رتینوئیک در جنین جوجه
ABSTRACT: Retinoic acid "one of the derivatives of vitamin A "has different morphogenic and teratogenic effects on developing organs. For this reason, the present study is an attempt to examine the effects of retinoic acid on limb bud ,eye and body axis of chick embryo in the stages of 11-12 Humburger and Hamilton. The experiments cartied out in this study was based on 140 white eggs which h...
متن کاملRetinoic acid is required for the initiation of outgrowth in the chick limb bud
BACKGROUND Retinoic acid (RA) is present in the chick limb bud, and excess RA induces limb duplications. Here, we have investigated the role of endogenous RA during chick limb development by preventing the synthesis of RA and testing the effect on various genes expressed during limb initiation and outgrowth. RESULTS We demonstrate that the stage 20/21 limb bud synthesizes didehydroretinoic ac...
متن کاملHensen's node from vitamin A-deficient quail embryo induces chick limb bud duplication and retains its normal asymmetric expression of Sonic hedgehog (Shh).
Both Hensen's node, the organizer center in chick embryo, and exogenous retinoic acid are known to induce limb duplication when grafted or applied to the host chick limb bud. Retinoic acid is known to be present in the node and has been proposed as the putative morphogen for chick limb development. Here, we report that Hensen's node from vitamin A-deficient quail embryo induces limb duplication...
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